The contraindication to taking cephalosporin is not to drink alcohol, whether beer, white wine or yellow wine, as long as there are also alcoholic beverages, they can react with the chemicals in cephalosporin, and this reaction is called disulfiram-like reaction. In mild cases, there will be clinical symptoms such as dermatitis, rash, skin redness, allergic papules, itchy skin, etc. In severe cases, there will be serious clinical symptoms such as palpitation, chest tightness, shortness of breath, panic, discomfort in the precordial area, etc. In the most serious cases, there will be clinical symptoms such as dizziness, headache accompanied by general weakness, nausea, jet vomiting, and even anaphylactic shock, so the biggest contraindication after taking cephalosporin is not to drink alcohol. In addition, the situation must be strictly observed after taking cephalosporin, for example, cold, spicy, seafood, hair products, etc. are relative contraindications for this drug.