Currently, Neocoronavirus nucleic acid cannot be self-tested for Neocoronavirus antigens that can be self-tested for Neocoronavirus. A positive antigen test requires a nucleic acid test for review. Neocoronavirus antigen test is detected by antigen and antibody binding reaction on a test paper as a way to determine if you are infected with Neocoronavirus. The antigen test is faster than the Neocoronavirus test and can be self-tested by individuals, but is less sensitive. Therefore, a positive antigen test needs to be retested with a nucleic acid test. Currently, nucleic acid testing is the most important diagnostic method for new coronavirus pneumonia, and most of the current viral nucleic acid test kits use fluorescent quantitative PCR. A negative nucleic acid test cannot exclude the possibility of infection, and repeated testing is required. No false positives have been reported with nucleic acid testing, and a positive test is diagnostic of novel coronavirus infection. Such cases need to be treated in isolation and released from isolation after nucleic acid conversion. During the new coronavirus pneumonia epidemic, personal protection is required, and people without contraindications are recommended to receive the new coronavirus vaccine in time to avoid new coronavirus infection. Tip: The “new coronavirus pneumonia” and “new coronavirus pneumonia” mentioned in this article have been renamed to “new coronavirus infection” on December 26, 2022, as announced by the National Health Commission.