Common factors for gastric cancer patients to vomit include pyloric obstruction, side reaction of radiotherapy, etc. They should consult doctor in time and take corresponding treatment to clarify the cause of disease. There are surgical treatment and drug treatment. After the pylorus is obstructed, it will reduce the patency of the stomach and affect the patient’s diet, which will cause the patient’s body to lose weight and malnutrition. Surgical treatment is needed to remove the lymph nodes in the obstruction area involved in the cancer, so as to ensure the effect of treatment as much as possible and prevent the recurrence and metastasis of gastric cancer. If the vomiting is caused by radiotherapy, acid-suppressing drugs, such as omeprazole, should be used as prescribed by doctor, which may alleviate the vomiting; if there is no obvious relief after taking omeprazole, central antiemetic drugs, such as palonosetron, etc., may be added, and the nausea and vomiting can be relieved obviously. If these two drugs do not provide relief, a triple antiemetic approach is needed, such as omeprazole, palonosetron, and fosaprepitant. Most of the patients can get obvious relief from nausea and vomiting after taking triple antiemetic treatment. When vomiting of stomach cancer occurs, one should consult the doctor in time to avoid delaying the condition.