There may be a conflict between the targeted drug and the New Crown vaccine. Due to the lack of relevant data, for the time being, the New Crown pneumonia vaccine is not recommended for patients taking targeted drugs. Patients taking targeted drugs mainly have malignant tumors, which are one of the more serious chronic diseases, and acute exacerbations of chronic diseases are not recommended for New Crown vaccination during treatment. Patients taking targeted drugs will usually have regular medical checkups to monitor the side effects of the targeted drugs and to understand the changes in their condition. After the drug treatment, the condition will enter a stable period. If the physical condition permits, and after the advice of experts, you can also consider receiving the new crown pneumonia vaccine, but after vaccination, you must pay attention to monitor the adverse reactions of the vaccine. If there are any uncomfortable symptoms, you should go to the hospital in time for examination and treatment under the guidance of the doctor. Tip: “New coronavirus pneumonia” and “new coronavirus pneumonia” mentioned in this article have been renamed to “new coronavirus infection” on December 26, 2022, as announced by the National Health Commission.