High cheekbones on one side and low cheekbones on the other side may be a normal phenomenon. If the difference between two cheekbones is big, it can be treated by autologous fat filling, local injection filling and zygomatic bone grinding. 1. Autologous fat filling: some of the excess fat of the body can be suctioned, and fat particles will be obtained, and then the fat particles will be injected into the zygomatic bone area by injection, so as to improve the problem of bilateral zygomatic bone asymmetry. 2. Local injection filler: hyaluronic acid can be filled locally, which can also improve the patient’s appearance, but hyaluronic acid has a certain effect cycle, which generally can be maintained for 5-7 months, and multiple injections are needed to maintain good results. 3. Zygomatic osteosynthesis: Zygomatic osteosynthesis can be treated through zygomatic osteosynthesis surgery, which can make the protruding zygomatic bone and the opposite side relatively symmetrical. The surgery is highly traumatic and risky, so caution is needed. When there is a big difference between one side of the zygomatic bone and the other side of the zygomatic bone, it is recommended to go to a regular hospital for treatment in time.