Cholecystectomy does not usually cause splenomegaly.
Cholecystectomy is a very common clinical procedure and common causes include acute and chronic cholecystitis and gallbladder stones. For some time after cholecystectomy, due to compensatory dilatation of the bile duct, patients may experience discomfort in the right upper abdomen, in addition to varying degrees of steatorrhea. However, it usually does not cause splenomegaly.
There are many clinical causes of splenomegaly, such as various infections, systemic lupus erythematosus, cirrhosis, portal hypertension, heart failure, hemolytic anemia, acute and chronic leukemia, lymphoma, multiple myeloma, Gosher’s disease, and glycogen storage disease. At present, cholecystectomy has not been found to cause splenomegaly.
It is recommended that the patient go to the hospital as soon as possible to find out the cause of splenomegaly and treat it accordingly.