Cracked tongue is generally referred to as furrowed tongue, and there is no clinical self-healing method, usually no specific treatment, in the case of acquired furrowed tongue, it is necessary to remove the cause of the disease and prevent infection. It is mostly considered to be related to vitamin B2 deficiency, niacin deficiency, psoriasis and other conditions. 1. Vitamin B2 deficiency: usually patients can follow the doctor’s instructions to use vitamin B2 preparations for treatment, and some patients also need to use niacin or vitamin B complex, which can play a better therapeutic effect. If the patient appears oozing phenomenon, can also be localized external 1% boric acid solution for wet compresses. 2. Niacin deficiency: usually patients can take oral niacin or niacinamide for treatment. After the improvement of symptoms, patients also need to actively regulate the diet, can be appropriate to increase lean meat, eggs, soy products, green leafy vegetables and other food intake, and patients also need to strengthen their own care to ensure oral hygiene, avoid sun exposure. At the same time, patients also need to supplement B vitamins, which is conducive to the improvement of the condition. 3. Psoriasis: patients can follow the doctor’s instructions to use 0.05% ~ 0.1% tazarotene gel and other vitamin A acid preparations for treatment, but also can use tacrolimus ointment, pimecrolimus ointment calcium-modulated neural phosphatase inhibitors or carboplatinol ointment and other vitamin D3 derivatives for treatment. Salicylic acid ointment, tar preparations, and anthralin ointment are also used to treat psoriasis. Also, some patients need to be treated with immunosuppressants such as methotrexate or biologics such as adalimumab and etanercept. If none of the above drugs are available, azathioprine and hydroxyurea are also available. It is recommended that patients with furrowed tongue take reasonable therapeutic measures and medications under the guidance of a doctor.