Childhood schizophrenia is not uncommon in outpatients, especially in those with a family history, often with their next generation developing the disorder at a younger age. In terms of treatment, pharmacotherapy remains the treatment of choice for the treatment of children with schizophrenia. Second-generation antipsychotics are the most predominantly used medications, such as risperidone, paliperidone, aripiprazole, olanzapine, and others. Relatively speaking, children with schizophrenia use relatively few medications and the doses of medications used may differ somewhat from those of adults. In addition to medication, psychological and social interventions and recreational training also play a very important role in the treatment of schizophrenia in children, and have a very important clinical value for the long-term prognosis of patients.