Currently, single-port laparoscopic surgery is more minimally invasive and aesthetically pleasing than traditional laparoscopic surgery, and many diseases in abdominal surgery can be treated with single-port laparoscopic surgery. Common diseases such as: appendix disease, gallbladder disease, gastrointestinal disease, hernia and spleen and liver disease can be treated with single-port laparoscopy. (1) Appendiceal diseases: such as acute appendicitis, chronic appendicitis, need to perform appendectomy first consider single-hole laparoscopic appendectomy. Laparoscopic appendectomy postoperative recovery, less trauma, the abdominal wall and intestinal tube will not have adhesion, will not cause long-term adhesive intestinal obstruction complications, and its surgery has something obvious. Abroad, in 1992, Pelosi et al. have reported 25 cases of appendicectomy with single-hole application of minilaparoscopy. By now the procedure is more mature, the following figure shows the single-hole laparoscopic appendectomy in our hospital. (2) Gallbladder diseases: benign diseases such as gallbladder stones, gallbladder polyps, etc. can be treated with single-port laparoscopic cholecystectomy. Also as early as 1997, Navarra et al. firstly applied single-port laparoscopic technique to the treatment of gallbladder diseases, and reported transumbilical single-port cholecystectomy. The following figure has single port laparoscopic cholecystectomy in our hospital. (3) Gastrointestinal diseases: benign masses of the stomach, such as gastrointestinal mesenchymal tumors; benign diseases of the esophagogastric fundus, such as reflux esophagitis; benign masses of the colon and early colorectal cancer; diverticula of the small intestine and other diseases can be relieved by single-port laparoscopy. 2007 Cobellis et al. reported the first case of laparoscopic-assisted transumbilical single-hole Meckel diverticulectomy; 2008 Bucher et al. reported l case of transumbilical single-hole Meckel diverticulectomy; 2008 Bucher et al. reported l case of transumbilical single-hole Meckel diverticulectomy. et al. reported l case of transumbilical single-port laparoscopic right hemicolectomy with surgical margins (>10 cm) and number of lymph nodes (33) meeting the surgical criteria. After that, there are also reports of single-port gastrointestinal surgery, single-port laparoscopic gastrointestinal surgery also has the advantages of minimally invasive, beautiful and fast postoperative recovery. The following pictures show some single-port laparoscopic gastrointestinal surgeries. Single-hole laparoscopic sigmoidectomy Single-hole laparoscopic resection of benign gastric masses (4) Liver and spleen diseases: such as liver cysts of large size need to be opened and drained, liver hemangiomas, splenic hyperfunction requiring splenectomy can also be used for single-hole laparoscopic surgery. Liver lobectomy and hilar bile duct surgery, liver malignant tumor surgery is difficult, should not choose single-port laparoscopic surgery. The figure below shows single-port laparoscopic splenectomy. Of course, general surgery common diseases such as hernia, goiter and so on, there are also domestic and foreign medical experts in the single-port laparoscopic surgery, surgeons continue to strive, the continuous development of minimally invasive surgery can give patients the safest, most effective, while minimizing trauma, the most suitable for the patient’s own means of treatment.