The semen is particularly thick in one pile is a manifestation of semen non-liquefaction. There are many reasons for semen non-liquefaction, generally common are the following: first, prostatitis, prostatitis can cause the secretion of sperm liquefaction factor to decrease, or urine stimulation leads to semen non-liquefaction. Second, seminal vesiculitis, which can cause an increase in coagulation factor, leading to semen non-liquefaction. Third, infection by pathogenic microorganisms, when the male reproductive organs are infected by microorganisms and bacteria, it can cause semen non-liquefaction. Fourth, when men lack trace elements such as magnesium and zinc in their bodies, it may also cause semen not to liquefy. Fifthly, mental factors, such as long-term anxiety, depression and tension, can cause semen to become non-liquefied, which can be further diagnosed through routine semen examination and genitourinary system ultrasound.