Bubbles in urine may be caused by physiological factors such as urination too fast, concentration of urine, or other diseases such as diabetic nephropathy and hypertensive nephropathy. 1. Physiological factors: if the urination process is more urgent may lead to strong impact of urine on the liquid surface, urine and air mixing, easy to form bubbles. In addition, usually drink too little water or urinate too much, may make the body of urine concentration, this time the protein concentration in the urine will become high, will also appear in the urine foam. 2. Diabetic nephropathy: the cause of diabetic nephropathy is not clear, and is considered to be related to renal microangiopathy. In addition to the manifestation of bubbles in urine, patients will also have edema, hypertension and other symptoms. 3. Hypertensive nephropathy: Hypertensive nephropathy is caused by high blood pressure which leads to the destruction of kidney structure, patients will have proteinuria, hematuria, hypertension, nocturia and other manifestations, due to the patients have proteinuria, so there will be the symptom of bubbles in urine. 4. Other: patients with urine bubbles are also considered to be caused by renal pelvis, nephrotic syndrome, interstitial nephritis, acute glomerulonephritis, extrusion syndrome and other diseases. If the bubbles are caused by physiological factors can not be treated, for the disease caused by the bubbles need to consult a doctor in a timely manner, follow the doctor’s advice to choose the appropriate measures for treatment.