There is a possibility that hives will heal on their own without medication, but the probability is relatively small, and in the process of not taking medication, it may cause the hives to worsen and make treatment more difficult. Hives is an allergic disease that develops as a direct result of exposure to an allergen. If the exposure is to food or inhalants, the symptoms can be quickly metabolized by the body after 1-3 days and this type of urticaria can heal itself even without medication. If the allergen in question is metabolized more slowly, such as if the drug or allergen persists, the symptoms tend to persist without medication and are difficult to heal on their own. The longer the duration of urticaria and the longer the course of the disease, the higher the total amount of medication required and the longer the treatment time. Most hives that do not heal on their own are bright red in color and do not fade easily.