Parkinson’s disease surgery is divided into two kinds of neuronal nucleus destruction surgery and deep brain electrical stimulation (DBS), the two surgical methods are different, and the cost difference is relatively large, the cost of neuronal nucleus destruction surgery is 30,000~50,000 yuan; the cost of deep brain electrical stimulation is more expensive, ranging from 100,000~300,000 yuan. 1. Nucleus destruction surgery: usually also called cytotoxic surgery, is through radiofrequency thermal coagulation or gamma knife and other guided destruction of abnormal nerve excitation nuclei in the brain to achieve the purpose of the surgery, but because of the sequelae and is a damaging surgery, is gradually reducing the application of the clinic. 2. Deep brain electrical stimulation: also known as brain pacemaker therapy, is the electrode implanted in specific nerve nuclei and nerve tissue location, through the release of pulse electrical stimulation of the nerves to achieve therapeutic effects, the advantages of its reversibility and adjustable pulse electrical strength, reducing the risk of surgery. Once Parkinson’s related symptoms are suspected, it is recommended to consult a doctor for treatment in time, and choose the appropriate treatment under the guidance of a doctor after a clear diagnosis.