MCHC is an abbreviation for mean red blood cell hemoglobin concentration, which is the average concentration of hemoglobin contained in each liter of blood. It is obtained by dividing the amount of hemoglobin per liter of blood by the specific volume of red blood cells per liter of blood, and the normal range is 320-360 g/L. MCHC has a very important reference value for the differential diagnosis of various anemic diseases. anemias with normal MCHC are aplastic anemia, acute blood loss anemia, most hemolytic anemias, myelopathic anemias such as leukemia, megaloblastic anemia and pernicious anemia, anemia due to chronic infection, inflammation, liver disease, pernicious tumors, rheumatic diseases. anemias with reduced MCHC are iron deficiency anemia, dyslipoprotein production anemia, iron granulocytic anemia, etc.