The main effect of the combination of chlorosartan and amlodipine is to treat hypertension combined with hyperuricemia. Chlorosartan mainly treats angiotensin II receptors, and during the administration of this drug can reduce the concentration of angiotensin II in the patient’s body, thus playing a role in lowering blood pressure, and during the administration of the drug can reduce the level of uric acid. The adverse effects of this drug are rare, and the occasional clinical adverse effects include headache and dizziness, nausea and diarrhea, tachycardia, and cough and sore throat. Postural hypotension and syncope may occur in very few patients. This drug is contraindicated in women with a history of allergy and breastfeeding, as well as in those with hyperkalemia. Amlodipine is a kind of calcium channel antagonist, can play the role of antihypertensive by dilating the arterial blood vessels, clinical adverse reactions include headache palpitations, lower limb edema, constipation, etc. Long-term use may lead to gingival hyperplasia in some patients. When taking this drug need to go through the doctor’s guidance and diagnosis, do not take this kind of drug privately.