Taking extended-release tablets (before the drug is metabolized) is not allowed to drink alcohol, due to the different speed of drug metabolism, it is generally recommended not to drink alcohol within 7 days. 1. Extended-release tablets of antibiotics, such as cefaclor, clarithromycin extended-release tablets, interact with alcohol, which can increase the burden on the liver and adverse drug reactions. 2. Extended-release tablets of non-steroidal anti-inflammatory drugs, such as diclofenac sodium, aspirin extended-release tablets, etc. and alcohol interaction can lead to palpitations, skin rashes, anaphylactic shock and other serious adverse reactions. 3. Extended-release tablets calcium antagonist drugs, such as nifedipine extended-release tablets and alcohol increase the antihypertensive effect, resulting in hypotension. Tachycardia or aggravate myocardial ischemia symptoms. In summary, during the period of taking extended-release tablets can not drink, if you need to drink alcohol under the guidance of a doctor according to the drug metabolism cycle in moderation, do not drink without authorization to cause adverse consequences.