Swelling by mosquito bites is particularly large, it is recommended to do a good job of local care, topical drug application, with oral medication, if necessary, timely hospital treatment. 1. Pay attention to local care: mosquito bites can cause itching, burning, swelling, it is recommended to do a good job of local care, to avoid scratching, irritation induced infection, resulting in aggravation of symptoms. 2. Topical medication: mosquito bites can cause angioedema, can be wrapped in a towel with ice for ice packs, apply glycerine lotion, mometasone furoate ointment and other drugs, can quickly reduce the inflammatory response, relieve itching. 3. Oral medication: If the symptoms are more obvious, you can also take oral loratadine, ebastine and other antihistamines, which can reduce the release of histamine in the skin and relieve itching. If the skin allergic reaction is more serious, continue to fail to subside, or due to scratching infection, pus, ulceration and other manifestations, it is recommended not to take the initiative to deal with, and promptly to the hospital dermatology department, ask the doctor to deal with the affected area.