Women’s bloating and hardness of the abdomen are considered to be related to intestinal obstruction, uterine fibroids, ovarian cysts, endometrial cancer, etc. Patients can follow the doctor’s instructions to use medication or surgical treatment. 1. Intestinal obstruction: patients with intestinal obstruction need to follow the doctor’s instructions for intravenous fluid replacement and gastrointestinal decompression, which can help reduce the pressure of the intestinal tube, accelerate the recovery of intestinal wall circulation and reduce the absorption of toxins. Some patients also need to cooperate with the doctor to perform intestinal resection and intestinal anastomosis, intestinal short-circuit anastomosis and other surgical treatments. 2. Uterine fibroids: usually asymptomatic people do not need treatment, accompanied by discomfort symptoms can be prescribed with gonadotropin-releasing hormone analogs, mifepristone to reduce the size of fibroids, but also available ibuprofen, aspirin and other non-steroidal anti-inflammatory drugs to ease the pain symptoms. When the fibroid is large and affects the life, myomectomy, hysterectomy and other surgical treatments are feasible. 3. Ovarian cysts: some patients with ovarian cysts can take short-acting contraceptives to prevent the occurrence of new cysts, such as deoxypregnene ethinyl estradiol tablets, drospirenone ethinyl estradiol tablets and so on. When the size of ovarian cysts is large and accompanied by uncomfortable symptoms, patients can cooperate with doctors to perform surgical treatments such as ovarian cystectomy and total hysterectomy. 4. Endometrial cancer: women with clear endometrial cancer need to follow the doctor’s instruction to remove the lesion through surgery, and after the surgery, radiotherapy, chemotherapy, interventional therapy and new type of targeted therapy can be chosen according to the condition. Some patients can also be treated with progesterone such as medroxyprogesterone and progesterone caproate during the treatment period. It is recommended that women with bloated and hard abdomen should consult a doctor for examination, so as to clarify the cause of the disease and then follow the doctor’s instructions for treatment, and should not use drugs indiscriminately on their own to prevent aggravation of the disease.