Severe craniocerebral injury is mostly seen in intracranial hematoma, extensive cerebral contusion and other conditions that lead to a sharp increase in intracranial pressure. It can be treated by keeping the airway unobstructed, lowering intracranial pressure and surgery. 1. Keep the airway open: observe the condition closely, check the respiration, pulse, blood pressure, consciousness and pupil changes at any time, and pay attention to whether there are new symptoms and signs. 2. Lower intracranial pressure treatment: through drugs to play the role of reducing intracranial pressure. For example, by mannitol, furosemide and other dehydration drugs, the water out, can reduce intracranial pressure. 3. Surgical treatment: patients with severe craniocerebral injury will be in coma for a long time, and their consciousness will be slowly impaired, and even brain hernia will occur. Patients with severe craniocerebral injury need to undergo craniocerebral CT for clear diagnosis, and should be operated as early as possible when there are surgical indications, such as hematoma removal, bone flap decompression, etc. It is recommended that patients with severe craniocerebral injury should undergo surgery as soon as possible. It is recommended that patients with severe craniocerebral injury should seek medical treatment in time and actively cooperate with the doctor’s treatment plan.