Breast pain, simple mammary epithelial hyperplasia is an early lesion of structural malformation of the breast. The main manifestations are breast swelling and pain and breast lumps. The following clinical features should be considered for the diagnosis of this disease. 1. Periodic pain and lumps in one or both breasts associated with menstruation in women of childbearing age. 2. Small granular masses with a non-hard texture can be palpated on examination. 3. The disease is self-limiting and recurrent in the process of development. Whole body imaging, breast tumor marker, tumor neuropeptide receptor imaging, liquid crystal thermogram, nipple overflow examination.