The effect of muscle relaxation or paralysis can appear 24 to 48 hours after Botox injection, so the effect of weakening dynamic wrinkles, decreasing muscle contraction, and decreasing sweat secretion can appear 2 days after injection. The effect of muscle reduction such as face slimming and calf slimming generally starts to be obvious only about 1 month after injection. Botulinum toxin injection has a gradual onset of effect, especially on the thinning of the face, thin calves and other muscle reduction effect is slowly appear, often through the comparison with the photo before the injection can be found obvious differences. There are very few people who have no effect after botulinum toxin injection, probably due to their own immune antibodies to botulinum toxin, making botulinum toxin ineffective. Reinjection of botulinum toxin should be carried out 4-6 months after the previous injection, and should not be repeated in large doses within a short period of time, otherwise it will easily cause the body to produce immune antibodies. For areas where the injection effect is a little unsatisfactory, a small amount of adjustment injection or supplemental injection can be done 1-2 weeks after the injection. Avoid biting hard food after injection to reduce the load of the bite muscle can make the effect of face slimming maintained longer. In addition, regular botulinum toxin face slimming injections every 4-6 months can also be maintained for a longer period of time after 3-5 injections. Can I leave immediately after Botox injection? After Botox injection, you should stay in the medical facility for at least 15 minutes to allow for immediate treatment of any adverse reactions. Can I do facial massage after Botox injection? Do not rub or massage the injection site for 48 hours after Botox injection to avoid spreading the Botox to muscles or glands other than the target muscle and causing unintended side effects. How long after the injection can I wash my face and apply makeup? Generally, you can wash your face, take a shower and apply makeup 6 hours after Botox injection. Can I smoke and drink after Botox injection? It is recommended to avoid smoking and drinking for 1 week after Botox injection. Can I lie down after Botox injection? It is recommended to avoid lying down for 4 hours after Botox injection to prevent the spread of Botox to the upper part of the cheek and cause sunkenness. Should I apply cold or hot compresses after Botox injection? Cold compresses can be applied immediately after Botox injection to reduce the pain after injection and also to relieve the spread of Botox. Do not apply hot compresses or take a bath for 2 days after injection to avoid spreading the Botox to muscles or glands other than the target muscle, which may cause unintended side effects. What are the dietary concerns after Botox injection? After botulinum toxin injection, abstain from eating seafood, spicy and stimulating foods, and avoid smoking and alcohol for 1 week.