Hard lumps with pain in breasts during puberty may be due to physiological reasons, or due to breast hyperplasia, mastitis, etc. Usually, general treatment, medication, surgery and other means can be used for treatment. 1. Physiological reasons: During puberty, due to the exuberant secretion of sex hormones in the body, the mammary glands will grow and develop rapidly under the stimulation of sex hormones, resulting in the appearance of lumps in the breasts, accompanied by a slight pain. Usually, there is no need to intervene too much. 2. Mammary hyperplasia: It may be due to endocrine disorders, resulting in an imbalance of estrogen and progesterone in the body, and overgrowth of mammary gland tissues, which will result in the appearance of hard lumps in the breasts, accompanied by a sense of pain. Vitamin E, bromocriptine, tamoxifen and other drugs can be used as prescribed by the doctor. 3. Mastitis: The patient’s breast tissue may be invaded by inflammation, which stimulates the normal tissue and leads to the gradual formation of hard lumps in the breast, accompanied by pain. Usually can be relieved by local hot compresses, if necessary, can follow the doctor’s instructions to use metronidazole, ceftazidime, indomethacin and other medications, the serious condition can be abscess incision and drainage. Other causes may also lead to hard lumps with pain in the chest during puberty, after excluding physiological causes, it is recommended to consult a doctor in a timely manner, and under the guidance of a professional doctor for appropriate treatment.