Cough aggravation after taking cough suppressants need to be based on the deterioration of the condition, co-infections, adverse drug reactions, such as increasing the dose, anti-infective or stopping the drug to seek medical attention and other measures. 1. deterioration: if the cough medicine is used in the early stage of the disease, the disease itself is in a period of progress, with the deterioration of the disease, even if the use of drugs can be aggravated by coughing manifestations, according to the instructions of the recommended dosage to comply with the doctor’s instructions can be appropriate to increase the dose. 2. Combined infection: Commonly include lung infection, can cause cough aggravation. Need to consult a doctor to check the type of infection, follow the doctor’s instructions to use penicillin and other antibiotics to control. 3. Adverse drug reactions: If the use of cough suppressants at the same time, the use of other drugs there are contraindications, may cause adverse drug reactions, need to stop the drug. It is recommended to consult a doctor in time to check the cause of the disease, and at the same time under the guidance of the doctor for targeted treatment.