Vitiligo is a type of vitiligo that requires oral glucocorticoid medication to control the progression of the disease, and is recommended to be combined with topical medication and physical phototherapy. Vitiligo generalized refers to vitiligo white spot area is relatively large, has reached level 4, white spot area greater than 50%, this type of vitiligo treatment is more difficult, often poorer therapeutic effect, need to actively cooperate with the doctor to take glucocorticosteroid drugs, such as methylprednisolone, prednisone and so on. But generalized vitiligo, and can not simply oral medication, often need to cooperate with local drugs to stop the spread of white spots more commonly used is the medium effect of topical hormone drugs, such as mometasone furoate cream, hydrocortisone butyrate cream, combined with light, such as lesions irradiation 308 excimer laser. Skin grafting can also be taken during the stabilization of the lesions. For generalized vitiligo control is more difficult, the patient must be timely to the hospital dermatology consultation, with the doctor for treatment, do not blind treatment.