Enhanced and thickened hepatic parenchymal echoes for more than 10 years may be due to fatty liver, cirrhosis, or hepatic fibrosis, and further examination is needed to clarify the cause. Normal liver parenchyma echoes are small, low and evenly distributed, whereas when there is disease in the liver, there may be enhancement and thickening of liver parenchyma echoes. Clinically, diseases such as fatty liver and cirrhosis are common causes of thickened liver parenchymal echoes. When fatty liver is present, there is fat deposition in the hepatocytes, causing changes in liver echogenicity. When cirrhosis and liver fibrosis occur, fibrous tissue proliferates in the liver, and the echoes will also be thickened and enhanced. Therefore, if you find that the liver parenchyma echogenicity is enhanced and thickened for more than 10 years, you should actively consult the doctor, improve the relevant examinations to make a clear diagnosis and then standardize the treatment.