A piece of skin on the calf is hard and itchy, considering that it is caused by ringworm, neurodermatitis, etc., and need to take medication and physical therapy. 1. ringworm: if the calf area appear ringworm patients will skin hard itching performance, patients need to be coated under the guidance of the doctor miconazole ointment, ketoconazole ointment and other antifungal ointment, or oral terbinafine, itraconazole and other antifungal drugs. 2. Neurodermatitis: patients with a piece of the calf area with neurodermatitis will also have the manifestation of skin hardening and itching, the patient can follow the doctor’s instructions to apply calcium-modulated phosphatase inhibitor ointment, such as pimecrolimus ointment, tacrolimus ointment, etc., or glucocorticoid ointment, such as halomethasone ointment, mometasone furoate ointment and so on. Some patients may also take oral antihistamines such as loratadine and cetirizine. In addition, patients can also effectively improve their symptoms through phototherapy. Patients with a piece of skin on the calf hardened itching should seek medical treatment in time, you can choose the appropriate measures under the guidance of the doctor to treat.