Ofloxacin and Roxithromycin can be taken together. 1. Ofloxacin is a western medicine. Commonly used dosage form of tablets, capsules, etc.; for quinolone antibacterial drugs; through the action of bacterial DNA rotamase A subunit, inhibit bacterial DNA synthesis and replication, and cause bacterial death; used for respiratory infections caused by sensitive bacteria, infections of the genitourinary tract, gastrointestinal tract infections, skin and soft tissue infections, and so on. Adverse reactions include: abdominal discomfort, diarrhea, nausea and vomiting, dizziness and headache, drowsiness, rash, mental abnormality, restlessness, confusion, hallucinations, tremor, hematuria, fever, eyelid edema, dry eyes and itching, etc. It is forbidden to those who have a history of allergic reaction to quinolone antimicrobials, pregnant and lactating women, and children. 2. Roxithromycin is commonly used in the form of tablets, capsules, granules, etc. It is a macrolide antibiotic. It is a macrolide antibiotic; it mainly combines with 50S ribosomal subunit of bacteria and inhibits the synthesis of bacterial protein by blocking the transpeptide effect and mRNA shift, so as to play an antibacterial role. Used for pharyngitis, tonsillitis, otitis media, respiratory tract infections, urethritis and cervicitis; soft tissue skin infections caused by sensitive bacteria. Adverse reactions are abdominal pain, diarrhea, nausea, vomiting, occasional rash, skin itching, dizziness, headache, liver function abnormalities, peripheral blood cell decline. It is forbidden to use for those who are allergic to this product or other macrolides, or those who take ergotamine or dihydroergotamine. The above two drugs have different mechanisms of action and different indications, and their use together does not reduce the efficacy of the drug, and there is a common effect, it is recommended that under the guidance of a physician, the use of reasonable medication.