The skull is a very important bone tissue in the human body, which plays an important role in protecting the brain, supporting the head and facial organs, and maintaining a normal and stable intracranial environment. Therefore, if a cranial defect occurs, it will be a safety threat to the brain and a very serious danger to the whole body, so early cranial repair is imperative. Cranial repair surgery is a routine procedure in neurosurgery and the technology is already mature. At present, the factor that has a great influence on the repair effect is the choice of skull repair materials. The skull repair material that is widely used clinically is titanium, some patients are worried about whether the total titanium skull can do MRI. This worry is still very necessary, although titanium alloy is a very common clinical material, but its performance is not very good, there are still many clinical problems, one of the significant problems is that titanium alloy material will affect the post-operative CT MRI and other medical examinations, out of the image will have metal artifacts, interference with the doctor’s diagnosis, of course, is not conducive to the subsequent treatment, which is very troublesome. In fact, the disadvantages of titanium materials are far from just this. In addition to this problem, titanium materials also have postoperative infection, rejection, causing scalp wear, material exposure, because of poor insulation caused by postoperative sensitivity to the external hot and cold environment discomfort and so on. There is also titanium alloy hardness is not high, may be deformed by external forces, once a 25-year-old boy skull defect repair with titanium mesh, later in a basketball game, the ball hit the head, titanium mesh directly collapse, causing serious consequences. So titanium material is not the ideal material for cranial repair. The more advanced and ideal material for cranial repair is the new polyetheretherketone PEEK material. This is a special polymer material with excellent performance, and its properties are comparable to those of human autologous cranial bone, which is a good way to overcome the above-mentioned problems that may arise from titanium alloy materials, and has achieved outstanding results in clinical practice. Our team extensively adopts PEEK as an advanced material, and we continue to innovate and upgrade the technology, optimize the design of the material, and make fine and personalized adjustments to improve comfort, prevent scalp abrasion, increase blood flow, maintain tissue activity, prevent temporal muscle atrophy, and enhance aesthetic appearance, and also introduce the concept of aesthetic plastic surgery. The PEEK cranioplasty can achieve anatomical integrity, functional perfection and aesthetic appearance, which is highly recognized and praised by patients.