Extracorporeal diaphragmatic pacemaker therapy Since the invention of the extracorporeal diaphragmatic pacemaker, this instrument has been used for resuscitation of respiratory failure and diaphragmatic rehabilitation of chronic obstructive pulmonary disease, and has also been continuously used for the treatment of IH with excellent results. The mechanism of diaphragmatic pacemaker for the treatment of erratic is that the electrical impulses it generates stimulate the phrenic nerve at the outer edge of the sternocleidomastoid muscle, interfering with the reflex arc of abnormal excitatory contraction of the diaphragm, thus restoring its normal rhythm and achieving therapeutic purposes. Western medicine treatment (1) electrolyte regulating drugs The literature reports that patients with electrolyte disorders, especially with hyponatremia, hypocalcemia, hypomagnesemia, hypokalemia, hypokalemia, etc., have been terminated or significantly relieved by electrolyte supplementation. The mechanism of hyponatremia is unknown, but the occurrence of IH is closely related to the decrease of blood sodium; the stress of nerve fibers and skeletal muscles is increased, i.e., the threshold is lowered, when the blood calcium and magnesium are low. A series of clinical manifestations of increased neuromuscular stress can occur, together with some patients with little food and prolonged bed rest, reduced gastric emptying and gastric fluid retention, and stimulation of the vagus nerve, which leads to the occurrence of IH. (2) Myorelaxants ① Baclofen, a derivative of the neurotransmission inhibitor γ-aminobutyric acid (GABA), mainly acts on the GABA receptors of spinal motor neurons, and its anti-erotic mechanism of action is not known. Chen Xiehui et al. suggested that: on the one hand, it may inhibit the nerve conduction, thus relieving the smooth muscle and diaphragm spasm to stop the eruption; on the other hand, it may inhibit the eruption center and stop the eruption through the sedative effect on the center. Dosage: 10mg orally twice a day; the maximum dose is 15mg three times a day. Chen Xiehui et al. applied 98% of total efficiency. Fan Lijing et al. believe that its mechanism of stopping eruption is: on the one hand, it acts on the spinal cord to inhibit the spinal reflex; on the other hand, it acts on the γ motor neuron to reduce the sensitivity of the spinal cord, thus blocking its reflex arc, relieving the spasm of the diaphragm, reducing the further stimulation of the phrenic nerve and vagus nerve of the spastic diaphragm; and it acts on the vascular smooth muscle to improve blood flow. Dosage: 60mg orally or by gastric tube, 3 times a day, after meals. (3) Antipsychotics ①Haloperidol 5mg intravenous or intramuscular injection 1-2 times/d, change to oral maintenance after improvement. ②Thorazine 25-50mg orally 3 times a day, but this method should be used with caution in elderly patients, especially those with cardiovascular disease. The anti-erotic effect of haloperidol and chlorpromazine may be related to their blocking of the upward reticular activating system and suppressing the excitability of the phrenic nerve. ③Lian Xiaoyu took neostigmine 1mg and chlorpromazine 25mg into 50ml of saline, and took 30-40ml orally on an empty stomach every 4-6h for the treatment of cerebral hemorrhage and postoperative cerebral tumor erratic reflux with obvious effect. (4) Antidepressants ①Doxepin 25-50mg orally 3 times a day. The mechanism of its anti-error may be through its central and peripheral anticholinergic effect on the one hand, and through the central sedative effect on the other hand, to achieve the effect of inhibiting the erratic center to stop the erratic. ②Amitriptyline 30mg orally 3 times daily. (3) Promethazine, 25mg/d gradually increased to 225mg/d. (5) Central excitatory drugs ① Ritalin 10-20mg intramuscular injection, repeated injection can be repeated for recurrence. The mechanism of terminating the erratic flow may be through the regulation of the central visceral nerves, or the phrenic nerves may be overexcited and reach the inhibitory state. It may be due to the excitatory effect of the drug on the respiratory center, which accelerates the deepening of respiration and increases the activity of the diaphragm, thus relieving the spasm of the diaphragm and terminating the eruption.