The generic name of the drug Nosyntho is sacubatril valsartan sodium tablets. The relationship between the dosage size of Sacubitril valsartan sodium tablets and the efficacy of treatment is not exact. The efficacy of the treatment depends on the correct and standardized treatment, use under the guidance of a professional doctor, do regular review follow-up, need to be titrated to the maximum tolerated amount according to the patient’s condition, so that the patient will benefit the most. Sacubitril valsartan sodium tablets are used for adult patients with chronic heart failure with reduced ejection fraction, which can reduce the risk of cardiovascular death and hospitalization for heart failure, and can be used to replace angiotensin II receptor antagonists, angiotensin-converting enzyme inhibitors, and can be used in conjunction with other medications for the treatment of heart failure, which has a significant therapeutic effect on patients with heart failure. Patients should describe in detail to the doctor the history of special allergies, physical condition, underlying diseases and recent medication use before using the drug to rule out contraindications and avoid the risk of serious medication. Sacubitril valsartan sodium tablets may cause renal impairment, some patients need to follow the doctor’s instructions for regular monitoring of renal function during drug administration to reduce the risk of drug use. When patients use the drug, it should be used under the guidance of a professional doctor and used in strict compliance with the doctor’s instructions to avoid blind use of the drug.