When you think of surgery, you think of bleeding. Blood transfusions can be life-saving, but they can also be fatal. At present, intraoperative or postoperative transfusion is the main reason for “blood shortage”. Since 2008, the Department of Thoracic Surgery has carried out more than one thousand cases of major surgery without blood transfusion, which has greatly saved blood supply and expenses. In the eyes of common people, thoracic surgery is a major operation, intraoperative bleeding is common. However, blood transfusion often causes panic among patients and their families, especially because there are many complications after transfusion, such as: transfusion-responsive diseases. Transfusion-induced infection with hepatitis C, AIDS and other blood-borne diseases. First, strengthen the perioperative treatment. For patients with preoperative anemia such as esophageal cancer and lung cancer who can be operated, intensive nutritional support or active treatment with iron or hematopoietic drugs should be given. Improve the diet after surgery. Early activity and exercise. Reduce postoperative complications. Secondly, emphasize the training of fine surgical technique operation. Standardized training of surgical techniques for surgical staff. Do not go on the stage without passing the technical operation. If the technique is not excellent, do not let go. Especially for the intraoperative vascular treatment, anatomical clarity, ligation carefully. The lymph nodes are cleared, the operation is standardized, and the technique is skillful. Extremely avoid bleeding and adequate hemostasis. For hypertensive patients intraoperative and postoperative control of hypotension. Maintain the patient’s reasonable body temperature. Third, actively carry out the application of new technologies. In recent years, thoracic surgery department through the introduction of training, study outside, strengthen academic exchanges and other multi-level, multi-channel internal introduction of outreach, the implementation of new technologies and new methods. Such as total lumpectomy pneumonectomy, segmental lung resection, thoracoscopic assisted radical esophageal cancer treatment, total lumpectomy mediastinal tumor, thymoma resection, etc.. The application of minimally invasive techniques has greatly reduced trauma and intraoperative bleeding. Patients recover quickly, and the hospitalization time is short while saving costs. Fourthly, autologous blood transfusion techniques are carried out. For patients with benign lesions that may cause intraoperative hemorrhage, the technique of autologous blood transfusion is used intraoperatively.