After menopause, the lining of the uterus does not usually thicken with estrogen supplementation. After menopause, if you supplement with estrogen alone, it may lead to thickening of the lining of the uterus, so you need to use progesterone under the guidance of your doctor, and the use of estrogen and progesterone together can prevent the lining of the uterus from overgrowing. Perimenopause may appear certain symptoms, such as hot flashes, excessive sweating, mood anxiety, etc., if the symptoms are more serious, you can choose hormone drugs to help relieve the doctor’s instructions; at the same time may also be accompanied by local symptoms, such as vulvar dryness, pain during sexual intercourse, urinary tract infections, etc., the use of hormone drugs as prescribed by the doctor, can also help women to relieve the symptoms. Postmenopausal women supplementing estrogen and progesterone must be under the guidance of a doctor to use medication.