A high apolipoprotein-b can be dangerous to health. There are many reasons for a high Apo-b ratio. Usually overeating, high salt and fat, prolonged smoking and drinking, and taking anti-epileptic drugs can lead to a high Apo-b. Apo-b is synthesized in the liver and is an important component of cholesterol and low-density lipoprotein. If Apo-b is high, it can cause hyperlipidemia, kidney disease, and predispose to coronary heart disease and cerebrovascular disease. High Apo-b increases the risk of coronary heart disease and cerebrovascular disease, so dietary and lifestyle modifications are needed to improve the condition, and medication can be taken if necessary. Apolipoprotein-b high is likely to cause abnormalities in the body’s lipid metabolism, resulting in hyperlipidemia, atherosclerosis and other diseases, so it is important to pay attention to diet and active treatment.