Apolipoproteins are the protein fraction of plasma lipoproteins, whose basic function is to transport lipids in the blood. Apolipoprotein b, due to its amino acid composition, is divided into Apo b48, the apolipoprotein of celiac particles, and Apo b100, the apolipoprotein of very low density lipoproteins and low density lipoproteins. Both types of apolipoproteins are produced by the liver. Since apolipoproteins exist on the surface of low-density lipoproteins, cellular recognition and uptake of low-density lipoproteins and very-low-density lipoproteins are mainly achieved through apolipoprotein b. Therefore, when apolipoprotein b increases, an increase in the levels of low-density lipoproteins and very-low-density lipoproteins can occur, which can significantly increase the incidence of coronary heart disease.