Telomeres are the repeating sequence part of DNA at the end of human cell chromosomes and their length determines the health status of the organism. Every time a cell divides, telomeres shorten, and when telomeres stop shortening, the cell dies. Telomerase can promote telomere growth, reverse cellular aging, restore circulation in the body, and maintain vascular elasticity and cellular activity. In recent years, telomerase has been used in medical aesthetics to remove facial wrinkles, such as head-lines, Kawasaki lines and nasal dorsal lines. However, telomerase wrinkle removal also has certain side effects, as follows: 1. Telomerase can cause some trauma to the skin during the injection process, and if redness and swelling occur after the procedure, you need to take the corresponding drugs according to the doctor’s requirements, and the swelling can gradually subside after about 3-5 days; 2. Telomerase activity is inhibited in normal human tissues and reactivated in tumors, and research shows that telomerase may be involved in malignant transformation of cells, especially it needs to be noted that it can make tumor cells in colorectum proliferate rapidly, such as excessive use of telomerase debridement may lead to adverse consequences such as intestinal cancer.