Most symptoms of lumbar 5/sacral 1 disc degeneration are mild and the condition is not serious. However, if the degenerative lesion affects the stability of the vertebrae, or if the patient’s symptoms are difficult to relieve and the condition is serious, prompt treatment is needed. Degeneration of the lumbar 5/sacral 1 disc, which is the disc between the lumbosacral 5 vertebrae and the lumbosacral 1 vertebrae, is a degenerative change, which is mostly due to age-related degenerative changes and can also occur in normal people. When the symptoms are mild, they are usually not serious, and can be relieved by resting, following doctor’s orders for pain relief, wearing a waist cincher, and limiting strenuous activities. However, the long-term development of intervertebral disc degeneration will affect the stability of the vertebral body to a certain extent, leading to a reduction in the cushioning ability of the vertebral body against strenuous movement, thus damaging the intervertebral disc during long-term strain or strenuous bending activities, leading to disc rupture, herniated nucleus pulposus, and pressure on the posterior part of the spinal cord causing lumbar pain, radiating pain in the lower extremities, with or without numbness in the lower extremities. Usually, it is necessary to actively carry out open surgery to remove the herniated disc, and if there is instability in the lower lumbar spine, it is necessary to actively carry out intervertebral implant fusion and internal fixation surgery. Patients are advised to avoid prolonged bending and strenuous lumbar exercises. Patients with lumbar 5/sacral 1 intervertebral disc degeneration should go to the hospital for timely examination and treatment under the guidance of the doctor.