Patients with high lymphocytes and low neutrophils without symptoms may be due to physiologic factors or due to viral infections, and asymptomatic patients are generally not given treatment. 1. Physiological factors: patients may have mildly high lymphocytes and low neutrophils, which are usually caused by physiological factors, with no specific cause of the disease, and do not cause symptoms; high lymphocytes and low neutrophils due to physiological factors usually do not require treatment. 2. Viral infections: viral infections will promote the increase of lymphocytes and decrease of neutrophils. Antiviral treatment such as oseltamivir and ganciclovir can be given. 3. High lymphocytes and low neutrophils can also be seen in acute lymphoblastic leukemia. Acute lymphoblastic leukemia may have symptoms such as hemorrhage, purpura, and infections in the early stage, or it may not be accompanied by the above symptoms, and the therapeutic drugs include cyclophosphamide, vincristine, etc. It is recommended to find out the cause of the disease in time. It is recommended to consult a doctor in time to identify the specific cause and receive targeted treatment or therapy under the guidance of a physician.