The main reason for localized anal soreness is the possibility of rectal and anal canal inflammation or anal sinusitis. Identification and diagnosis of the above diseases requires anoscopy and, if necessary, electronic colonoscopy as well as pathological examination to make a clear diagnosis. If the disease is caused by proctitis or anal canal inflammation, localized soreness and pain in the anus, accompanied by increased discharge, anti-inflammatory and symptomatic treatment is needed. You can choose to retain the Chinese medicine enema and take oral monkey head bacteria extract granules. If ulcerative colorectitis is suspected, oral administration of mesalazine extended-release granules and anal administration of mesalazine suppositories are required after pathological tests. If the discomfort is caused by simple anal sinusitis, you can choose metronidazole suppositories for anal plugging and anti-inflammatory treatment, or you can surgically open the local inflamed anal sinus to relieve the symptoms of inflammation.