The first is that it may be a condyloma, a contagious disease caused by the human papillomavirus, which develops in the genitals and around the anus, with cauliflower-like protrusions that are painful and itchy, and need to be treated with laser and electrocautery. Secondly, it may be caused by anal eczema, which is a small blister-like object around the anus, with a flushed base and itchy, scratching and breaking, oozing and pus, and can be treated with Denide cream, which is difficult to cure and easily recurs. Thirdly, it may also be hemorrhoids, which can be severe with pain, itching and bleeding, and it is not excluded that it is caused by anal papilloma or anal fissure.