Muscle pain after stopping statins, such as stopping the drug for a short period of time or the pain is mild can be further observation. Patients with severe pain should seek medical attention to check for serious adverse effects such as rhabdomyolysis, and follow the doctor’s instructions for medication and symptomatic treatment after a clear diagnosis. Statin-associated myopathies mainly include myalgia, myositis and rhabdomyolysis. Among them, rhabdomyolysis is the most serious adverse reaction, in addition to the symptoms of muscle pain is also accompanied by blood creatinine and creatine kinase significantly increased. Usually, the symptoms of muscle pain can be relieved or recovered within 1~2 weeks after stopping the medication. Drinking more water can help the metabolism of the medication or applying hot compresses appropriately to relieve the pain. If prolonged unrelieved should consult a doctor, check the blood creatinine and creatine kinase levels, serious elevation to more than 10 times the patient to consider rhabdomyolysis. Under the guidance of the doctor to correct electrolyte disorders, sodium bicarbonate alkaline supplementation and other symptomatic treatment. Patients should pay attention to reasonable exercise, excessive exercise will aggravate the adverse effects of statins and delay the healing process. At the same time, light diet, avoid greasy, spicy diet. If there is any discomfort after taking statin drugs, consult a doctor in time.