Boils between the vaginal opening and the anus can be caused by folliculitis, perianal abscess, Bartholin’s gland cysts, hemorrhoids and other diseases. 1. Folliculitis: poor local hygiene, infection with bacteria and other pathogens can cause localized folliculitis, which can appear between the vaginal opening and anus like boils, itching, pain and other uncomfortable symptoms. 2. Perianal abscess: after infection of anal crypt, it can spread to the perirectal space along the anal glands and lymphatic drainage direction, and can form abscess locally, which can be manifested as boils between the vaginal opening and the anus, and can be accompanied by pain, fever and chills, and other symptoms. 3. Bartholin’s gland cysts: Bartholin’s glands, also known as vestibular glands, are distributed on both sides of the vagina and have secretion function. When the gland ducts are blocked, it can lead to the accumulation of glandular fluids and the formation of cysts, which can be manifested as boils between the vagina and the anus. 4. Hemorrhoids: Hemorrhoids can also occur between the anus and the vulva when they are large and oedematous or form blood clots, which can cause pain and blood in the stool. When boils occur between the vaginal opening and the anus, you should consult a doctor in time, and under the guidance of a specialist, you can actively carry out the appropriate treatment to help alleviate the discomfort and avoid aggravation of the condition.