There is no absolute fastest way to recover from a crooked mouth. First of all, it is necessary to make a clear diagnosis, for example, cerebral infarction, Guillain-Barré syndrome, idiopathic facial nerve palsy, etc. It is necessary to address the cause of the disease, and medication and surgical treatments can be used to alleviate the symptoms. 1. Cerebral infarction: The blockage of blood vessels causes nerve ischemia and loss of nutrients, leading to facial nerve paralysis and causing symptoms of crooked mouth. Thrombolysis with alteplase can be used in the acute stage, and anti-platelet, lipid-lowering and plaque stabilization with aspirin and atorvastatin can be used in the recovery stage. If necessary, specific treatment such as endovascular thrombolysis can be taken to improve the symptoms. 2. Guillain-Barré syndrome: Facial nerve damage due to infection, autoimmune factors, etc., causing symptoms of crooked mouth, which requires early immunotherapy and neurotrophic therapy under the guidance of a doctor, such as the use of immunoglobulin, methylcobalamin, vitamin B1, etc., and neurological rehabilitation after stabilization of the condition. 3. Idiopathic facial nerve palsy: glucocorticoids such as prednisone and dexamethasone can be used to reduce facial nerve swelling. In severe cases, surgery such as facial nerve decompression should be considered. There are many causes of crooked mouth, it is recommended to consult a doctor in time to find out the cause of crooked mouth and standardize the treatment under the doctor’s guidance.