The occurrence of black-eyed fainting and sweating is caused by transient hypoxia and ischemia of the brain, which can be seen clinically in a variety of cardiovascular and cerebrovascular diseases, endocrine diseases, and hematologic diseases. For example, the patient has paroxysmal arrhythmia, cerebral vascular spasm, transient hypoglycemia, severe anemia, etc. The clinical diagnosis needs to be further clarified by combining the patient’s previous relevant medical history with clinical examination and related tests. In the process of history taking, attention should be paid to the patient’s precipitating factors, duration, related concomitant symptoms and family history. The physical examination should pay attention to the pulse rate and blood pressure of the patient, and whether the patient has pallor and dyspnea, especially whether the patient is suffering from postural hypotension. In the course of the examination, we need to make focused and individualized arrangements for the examination plan in conjunction with the patient’s examination and physical examination. Treatment should actively control the controllable causes, avoid the triggering factors, and actively prevent and treat the patient’s related complications.