Usually high fever accompanied by vomiting is caused by the following etiologies: 1. The most common etiology is digestive system diseases, such as acute gastroenteritis, acute pancreatitis, peritonitis and appendicitis caused by acute cholecystitis, which require the application of the following drugs: 1. Application of symptomatic antipyretics non-steroidal anti-inflammatory drugs, such as indomethacin, compound amylin barbiturates and fenpropathrin, somatostatin, analgesic can be applied. 2. Taking western drugs such as proton pump inhibitors and compounded bismuth such as aluminum thioglycollate, omeprazole, rabeprazole can relieve vomiting. Second, such as common diseases triggered by high fever or accompanied by vomiting violent aggravation obvious, but also may be acute viral encephalitis, acute encephalomyelitis, etc., when such as the examination of brain CT will have obvious changes, at this time will also be accompanied by headache, dizziness and other neurological diseases. Thirdly, if high fever accompanied by vomiting is caused by certain drugs and food poisoning, symptomatic treatment should be selected according to the cause of the disease and blood test.