It is best not to take a shower on the day of the third vaccination. It is best not to take a shower for 24 hours after vaccination to avoid infection at the injection site and to prevent catching a cold. Since the skin at the site of the needle eye is not completely closed after the vaccination, localized infections are likely to occur after bathing and contact with water. On the other hand, bathing may cause the body to catch a cold, which may lead to fever and other discomforts, in which case it is not easy to distinguish whether an adverse reaction to the vaccine has occurred. As redness, swelling and hard nodules may occur after vaccination, excessive stimulation and pressure should also be avoided when bathing, and the eye of the needle needs to be kept clean after bathing to avoid infection, and once an adverse reaction occurs, it should be taken to the hospital in a timely manner to avoid the development of the condition.