Gallbladder palpation can be divided into one-handed gliding palpation and hook finger palpation. 1. One-handed gliding palpation: when using one-handed gliding palpation of the gallbladder, the examinee takes a supine position with legs flexed, fully exposing the abdomen. The examiner is located on the right side of the examinee, the four fingers of the right hand are together, the metacarpophalangeal joints are straightened, and the right side of the rib cage is placed roughly parallel to the right side of the examinee’s right upper abdomen. The subject is instructed to breathe slowly and deeply, and when the subject exhales deeply, the examiner’s fingers press deeper into the abdomen. Ask the subject to inhale deeply, the examiner’s finger glides under the gallbladder to palpate the displaced gallbladder. 2. Hook finger palpation maneuver (Murphy’s sign examination): the examiner puts the left palm flat on the lower part of the right chest of the examinee, and presses on the point of the gallbladder under the right costal margin with the hook of the thumb, and then instructs the examinee to inhale slowly and deeply. In the process of inhalation, when the inflamed gallbladder moves downward and touches the thumb that presses hard, it can cause severe tenderness or hold the breath due to pain, which is positive for Muphy’s sign, and is mainly seen in acute cholecystitis. It is recommended that patients with gallbladder discomfort should go to a regular hospital for consultation.