Injecting a therapeutic dose of botulinum toxin is safe, but if too large a dose of botulinum toxin is injected at one time, it may lead to a systemic toxic reaction. Therefore, Botox injections should go to regular medical institutions and use regular products approved by the State Food and Drug Administration. Is it true that the more Botox injected at one time, the better the effect and the longer it lasts? Botulinum toxin injection for facial wrinkles, if the injection dose is large, it is easy to cause facial expression stiffness, but affect the cosmetic effect. After the injection of Botox reaches a certain dosage, even if the dosage is increased, the effect will not be significantly extended. Will multiple injections of Botox cause dependence? Will the wrinkles worsen if I stop injecting? Botox injections do not have a dependency, even if you stop using it, there will not be any aggravation, the wrinkles will just go back to the baseline level, but as the person continues to age, it gives a feeling of aggravation. How long is the interval between Botox injections before I can inject again? Generally there is a minimum of 3 months between Botox injections. (Excluding the time for adjustments by small injections within a short period of time after the first injection) Do all facial wrinkles disappear after Botox injection? If the wrinkles are dynamic wrinkles that appear only after the muscles contract when the face makes an expression, the wrinkles can be flattened by Botox injection. If the wrinkles are static wrinkles that are present when the face is calm, then Botox injections can only make the wrinkles lighter and need to be combined with other treatments such as filler injections in order to flatten the wrinkles.