Hematocrit refers to the sedimentation rate of red blood cells, and the high level of this index is related to surgical trauma, anemia, chronic nephritis, malignant lymphoma, etc., which can be treated with medication or surgery according to the doctor’s prescription. 1. Surgical trauma: some patients may have rapid blood sedimentation rate due to stress reaction caused by surgical trauma, if there is no complication, it will return to normal within 2 to 3 weeks, and no special treatment is needed. 2. Anemia: anemia can be improved by supplementing elements or factors needed for hematopoiesis as prescribed by doctors, such as vitamin B12, ferrous sulfate, ferrous gluconate and so on. Some patients with serious condition or unsatisfactory drug treatment can be treated by allogeneic hematopoietic stem cell transplantation, splenectomy and other surgical methods. 3. Chronic nephritis: patients can use diuretics such as hydrochlorothiazide and furosemide, angiotensin-converting enzyme inhibitors such as enalapril and benazepril, and angiotensin II receptor antagonists such as chlosartan and valsartan to lower blood pressure and eliminate edema as prescribed by the doctor. Some patients with serious condition can be treated with renal transplantation, hemodialysis, peritoneal dialysis and other treatments as prescribed by doctors. 4. Malignant lymphoma: patients with malignant lymphoma should actively cooperate with doctors to carry out radiotherapy and chemotherapy, and commonly used chemotherapeutic drugs include vincristine, doxorubicin and so on. Some patients can be treated with monoclonal antibody, interferon or hematopoietic stem cell transplantation, CAR-T cell immunotherapy as prescribed by doctors. There are many causes of high erythrocyte sedimentation rate, such as rheumatic diseases, tuberculosis, acute infections, tissue injury and so on. It is recommended that the patient undergo further detailed examination to clarify the cause of the disease and then follow the doctor’s instructions for treatment. Usually, the erythrocyte sedimentation rate can return to normal after the disease is controlled or cured.