The medication of the closed injection is very simple, generally glucocorticoids (such as prednisolone acetate) plus local anesthetics (such as lidocaine), can also be coupled with Vit B12. Side effects of the closed injection: First: the risk of needle infection; Second: glucocorticoids have a tendency to increase blood sugar. If you do not often play closed, occasionally play a few times, there should be no great harm to the body, generally there are the following cases should be carefully considered: 1, diabetic patients; 2, gastric, duodenal ulcer active; 3, active tuberculosis; 4, patients with severe hypertension; 5, patients with severe osteoporosis. Regularly applied in large quantities can lead to centripetal obesity.