Colchicine generally has no significant effect on uric acid, so taking colchicine once can check uric acid. Colchicine is a kind of drug mainly used to relieve the symptoms of gout during acute attacks, the drug does not reduce the patient’s uric acid, and does not affect the process of uric acid production, dissolution and excretion, so patients can test blood uric acid after taking colchicine. Before testing blood uric acid should pay attention to fasting, to avoid the first 3 days of intake of food containing high purine, such as seafood, beans and legumes, animal offal, etc. In addition, the test 24h urine uric acid can help distinguish between the blood uric acid elevation is caused by the generation of increased or decreased excretion, in order to guide the clinical use of drugs. It is recommended that patients who need to test uric acid go to the rheumatology and immunology department and endocrinology department of regular hospitals for detailed consultation.